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Jonathan Afilalo Selected Research

COVID-19

1/2023Proteome-wide Mendelian randomization implicates nephronectin as an actionable mediator of the effect of obesity on COVID-19 severity.
1/2023Circulating proteins to predict COVID-19 severity.
9/2022The dynamic changes and sex differences of 147 immune-related proteins during acute COVID-19 in 580 individuals.
1/2022A randomized controlled trial of renin-angiotensin-aldosterone system inhibitor management in patients admitted in hospital with COVID-19.
1/2021A Neanderthal OAS1 isoform protects individuals of European ancestry against COVID-19 susceptibility and severity.

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Jonathan Afilalo Research Topics

Disease

31Frailty
05/2024 - 11/2010
8Aortic Valve Stenosis (Aortic Stenosis)
10/2020 - 07/2014
5Cardiomyopathies (Cardiomyopathy)
05/2024 - 09/2007
5Heart Failure
11/2023 - 08/2007
5COVID-19
01/2023 - 01/2021
4Sarcopenia
05/2024 - 11/2019
4Atrial Fibrillation
01/2021 - 11/2009
4Cardiovascular Diseases (Cardiovascular Disease)
01/2020 - 07/2010
3Cognitive Dysfunction
10/2020 - 11/2019
3Delirium
01/2020 - 01/2019
2Myocarditis (Carditis)
11/2022 - 01/2021
2Malnutrition (Nutritional Deficiencies)
01/2021 - 01/2020
2Heart Arrest (Cardiac Arrest)
01/2021 - 10/2015
2Stroke (Strokes)
01/2020 - 01/2008
2Coronary Artery Disease (Coronary Atherosclerosis)
05/2016 - 02/2013
2Right Ventricular Dysfunction
03/2014 - 01/2013
2Myocardial Infarction
07/2010 - 01/2008
2Coronary Disease (Coronary Heart Disease)
01/2008 - 08/2007
1Critical Illness (Critically Ill)
01/2023
1Disease Progression
01/2023
1Obesity
01/2023
1Infections
09/2022
1Renal Insufficiency (Renal Failure)
01/2022
1Cardiogenic Shock
01/2021
1Heart Block
01/2021
1Hemorrhage
11/2020
1Sleep Deprivation
01/2020
1Fatigue
11/2019
1Body Weight (Weight, Body)
10/2019
1Pulmonary Hypertension
01/2019
1Weight Loss (Weight Reduction)
05/2017
1Hypotension (Low Blood Pressure)
10/2015
1Pulmonary Edema
10/2015
1Hypertension (High Blood Pressure)
07/2013
1Sclerosis
02/2013
1Wounds and Injuries (Trauma)
01/2010
1Osteoporosis
11/2009
1Acute Coronary Syndrome
08/2007
1Rhabdomyolysis
08/2007
1Polyps
04/2007
1Ischemic Stroke
04/2007
1Adenoma (Adenomas)
04/2007

Drug/Important Bio-Agent (IBA)

7Proteins (Proteins, Gene)FDA Link
12/2023 - 10/2019
3Biomarkers (Surrogate Marker)IBA
12/2018 - 11/2010
2pro-brain natriuretic peptide (1-76)IBA
05/2024 - 12/2023
2Brain Natriuretic Peptide (Natrecor)FDA Link
05/2024 - 01/2022
2CytokinesIBA
01/2023 - 09/2022
2Immune Checkpoint InhibitorsIBA
11/2022 - 01/2021
2omega-Chloroacetophenone (Mace)IBA
01/2021 - 08/2007
2Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
01/2008 - 08/2007
1Cytokine Receptors (Cytokine Receptor)IBA
01/2023
1ProteomeIBA
01/2023
1RNA (Ribonucleic Acid)IBA
01/2023
1nephronectinIBA
01/2023
1Nucleic AcidsIBA
09/2022
1insulin receptor-related receptor (IRR)IBA
01/2022
1Leucine (L-Leucine)FDA Link
01/2021
1Protein Isoforms (Isoforms)IBA
01/2021
1AnticoagulantsIBA
01/2021
1Biological FactorsIBA
01/2020
1AlbuminsIBA
01/2020
1Indicators and Reagents (Reagents)IBA
11/2019
1Bromocriptine (Parlodel)FDA LinkGeneric
01/2019
1ProlactinIBA
01/2019
1A 17 (A-17)IBA
12/2018
1Nitroglycerin (Dynamite)FDA LinkGeneric
10/2015
1Furosemide (Lasix)FDA LinkGeneric
10/2015
1NitratesIBA
10/2015
1AndrogensIBA
06/2014
1Sex Hormone-Binding GlobulinIBA
06/2014
1Testosterone (Sustanon)FDA Link
06/2014
1Luteinizing Hormone (Lutropin)FDA LinkGeneric
06/2014
1ElementsIBA
03/2014
1Diphosphonates (Bisphosphonates)IBA
11/2009
1Alendronate (Alendronate Sodium)FDA LinkGeneric
11/2009
1Lamin Type A (Lamin A)IBA
09/2007
1Transaminases (Aminotransferases)IBA
08/2007
1Creatine Kinase (Creatine Phosphokinase)IBA
08/2007

Therapy/Procedure

20Transcatheter Aortic Valve Replacement
05/2024 - 07/2014
10Coronary Artery Bypass (Coronary Artery Bypass Surgery)
01/2021 - 07/2010
5Length of Stay
01/2021 - 01/2017
5Therapeutics
01/2021 - 08/2007
2Polypharmacy
01/2020 - 12/2019
2Cardiac Rehabilitation
01/2020 - 11/2019
1Lung Transplantation
11/2023
1Walkers
01/2022
1Erythrocyte Transfusion
11/2020
1Bed Rest (Bedrest)
01/2020
1Vascular Surgical Procedures
01/2019
1Prostheses and Implants (Prosthesis)
01/2019
1Heart Transplantation (Grafting, Heart)
12/2018
1Operative Surgical Procedures
05/2017
1Cardiac Surgical Procedures
05/2017
1Cardiac Resynchronization Therapy
06/2016
1Cardiac Resynchronization Therapy Devices
06/2016
1Implantable Defibrillators (Implantable Cardioverter-Defibrillator)
06/2016
1Noninvasive Ventilation
10/2015
1Denervation
07/2013
1Sternotomy
01/2010
1Negative-Pressure Wound Therapy
01/2010